Congratulations to Ms. Ploychom Poonlak, an alumnus of Master's degree, for publishing the work of Tier 1 International Journal.

Congratulations to Ms. Ploychop Poonlak, an alumnus at the Master of Science in Medical Technology, Faculty of Universal Medicine, Naresuan University, on the occasion of the publication of her research in the International Journal (Tier 1), which was mentored by Associate Professor Dr. Chiraphas Jongjitwimol. This study examined the carO gene diversity in carbapenem-resistant Acinetobacter baumannii (crab) bacteria, which the World Health Organization (WHO) classifies as the most critical hospital pathogens. The researchers used molecular biology methods.Charting evolution and using the AlphaFold2 program to predict the three-dimensional structure of the CarO protein, it was found that the resistant group had a specific form of the CarO gene mutation, which clearly affected the protein structure, the external protein loop region, and the channel of the protein, in line with the function of the drug pathway. In addition, it was found that the mutational patterns of the infection in Thai and Myanmar patients were consistent, reflecting the spread of drug-resistant infection in the region, which is beneficial for the public health system to continue monitoring. Read the full study athttps://doi.org/10.3390/antibiotics15090828

#AcinetobacterBaumannii #CarbapenemResistance #CarO #AntimicrobialResistance